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Table 1 Number of transcript clusters whose expression is disturbed at different cut-off threshold p values

From: Transcriptome and metabolome analysis of liver and kidneys of rats chronically fed NK603 Roundup-tolerant genetically modified maize

p value

Liver NK603+R

Kidneys NK603+R

Liver NK603

Kidneys NK603

Random

Liver Roundup

Kidneys Roundup

0.05

2126(0.83)

2337(0.78)

2119(0.86)

3176(0.58)

1835(0.98)

8606(0.21)

8656(0.21)

0.01

393(0.83)

543(0.67)

425(0.83)

838(0.43)

380(0.96)

4224(0.08)

4447(0.08)

0.001

29(0.83)

58(0.58)

54(0.58)

127(0.29)

31(0.95)

1593(0.02)

1894(0.02)

0.0001

1(0.61)

8(0.40)

7(0.77)

14(0.25)

1(0.95)

630(0.006)

764(0.005)

0.00001

0

1(0.15)

1(0.24)

2(0.11)

0

230(0.002)

219(0.002)

  1. Transcriptomics results of liver and kidneys from rats fed NK603 GM maize either with (NK603+R) or without (NK603) Roundup application during the cultivation cycle summarizing the number of genes whose expression was altered at different p value thresholds. The number in superscript parenthesis is the maximal q value (calculated using Benjamini–Hochberg method according to corresponding to the number of genes found disturbed at increasing (0.05 to 0.00001) p value stringency. A statistical analysis of simulated random samples was also performed to estimate effects that would be expected to arise by chance. The number of genes disturbed by the Roundup treatment in the same experiment is given for comparison