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Table 1 Overview of relative in vitro EA endocrine potencies (agonistic and antagonistic) of test substances

From: Screening for potential endocrine disruptors in fish: evidence from structural alerts and in vitro and in vivo toxicological assays

Activity

Relative potency

Number of substances

Very high

≥1

35

High

0.1–1

66

Moderate

0.001–0.1

110

Weak

0.00001–0.001

96

Very weak/inactive

<0.00001

437

Total number of substances

 

744

  1. Relative potency: substances were categorized based on their in vitro potencies in individual tests, relative receptor-binding affinities, or effect concentrations relative to positive controls, ethinylestradiol (estrogenic) or testosterone (androgenic), respectively